ABSTRACT
Abstract: Background & Objective: Drug utilization research studies are effective tools that help in evaluating the drug prescribing trends, efficiency of hospital formularies. Proton pump inhibitors (PPI) are one of the most frequently prescribed classes of drugs. However because of their High efficacy & easy availability irrational use and unnecessary exposure is high. This study is designed to identify such problems and to promote rational and judicious use of PPIs. Methodology: A retrospective cross-sectional study was conducted at the S.S Institute of Medical Science and Research, Davangere. Patient medical records with of PPIs prescription were analysed for drugs used including name of the drug, dosage schedule, duration of treatment and concomitant medication. Rationality of prescriptions was evaluated by referring to the indications of PPI use By National Formulary of India; 2011. Results: 216(54%) cases on PPI medications were selected to for our study. Pantoprazole was prescribed in majority of 68% followed by Rabiprazole 16%, Esmoprazole in 13% and then by Lansoprazole in 3% of patients. In our study indications for PPI prescriptions were acute gastritis (4%), GERD (5%), as preoperative medication (11%) and along with NSAIDS (24%) but majority 56 % of PPI prescriptions had no clear indication. Among concomitant drugs used, Antimicrobials were the most commonly (68%) used followed by nonsteroidal anti-inflammatory drugs (24%) and other drugs like Antihypertensive (9%) and Antiemetic (13%). Conclusion: PPIs are one of the most commonly prescribed drugs. But most of the prescriptions had no proper indications hence irrational. Creating awareness about judicious use of PPI is a necessity.
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Objectives: To assess polypharmacy and patient’s knowledge regarding antihypertensives in Gynaecology and obstetrics department. Materials and Methods: This is a prospective comparative study carried out in Gynecology and Obstetrics department in two tertiary care hospitals. A interaction was done with consultants, post graduate students patients and patient’s attendants and the readings were taken. Results: A total of 200 prescription were studied and the average number of per prescription was 2.47%, poly pharmacy in 122/200, adequate knowledge was in 139/200 patients. Conclusion: The incidence of poly Pharmacy was more in our set of studies, patients compliance/adequate knowledge was good only among educated patients. The concerned health care can be improved by prescribing rational and required prescription and by motivating patients and patient’s attender, regarding the intake of drugs.
ABSTRACT
Objectives: To evaluate the drug utilization of antihypertensive in obstetric practice two tertiary care hospitals in Gulbarga city. Material & Methods: A prospective cross-sectional study was conducted for 2 years in obstetric departments of Government General Hospital and Sangameshwar Teaching Hospital, Gulbarga. W.H.O. basic drug indicators were used for studying the prescribing trends and interviewing the patients. Results: A total of 200 prescriptions were studied and the average number of drugs per prescription was 2.47. 1.89% of generics and 49.59% of essential drugs were prescribed. 98.15% were non generic names used. The average consulting time given per patient was 9 mins 8 secs. 69.5% of the patients knew their dosage schedule and this was related to their education status. 13% were irrational prescription. The frequency of use of Nifedipine was highest followed by Benzathiazide + Triamterene, Amlodipine, Furosemide, Methyldopa and Spiranolactone etc. The use of the safest drug, Methyldopa was among only 4% of patients. 66.28% of prescribes drugs were available in hospital pharmacy. Conclusion : The incidence of poly pharmacy was high. Patient compliance is good only among educated patients. Irrational prescriptions were few. The availability of drugs in the hospitals was not satisfactory. The present healthcare can be improved by advocating rational drug prescribing patient education and improving the facilities in the hospitals.